Brief Introduction：
Research Center for Resource Insects and Biotechnology (RCRIB)，was founded in 1978, of which the predecessor was known as Nematodes Research Group. It was renamed as the Biotechnology Research Group in 2000 and in 2009 it was renamed as the present name.

Research Area：
(1) The research, industrialization and application of the novel biological insecticide - entomopathogenic nematodes;
(2) The research and utilization of resource insects (medicinal insect - the Hepialidae insect, pollinator - bee, feed insect-house fly) and their functional genes;
(3) The research and application of biotechnology (fermentation engineering, genetic engineering, cell culture, biochemistry, etc.).

Research Progress：
In recent 20 years, the research center has undertaken more than 80 important research projects, including international cooperation projects [such as projects from Australian Centre for International Agricultural Research (ACIAR), International Foundation for Science (IFS), the European Union Fifth and SeventhFramework Program (FP5 and FP7), Flemish Interuniversity Council and UK Department for International Development (DFID)], projects supported bythe National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province, and other projects supported by local government.
The research center won 9 prizes awarded by national and provincial government; applied for 57 national invention patents, 44 of which were authorized; applied for 6international invention patents, 2 of which were authorized; published more than 150research papers including more than 50 papers in SCI source; participated in writing 3 monographsin Englishincluding “Entomopathology Nematology”, “Application of Entomopathogenic Nematodes”, “Mass production of Beneficial organisms”, and 1 monographof “Biological Control for Pest” in Chinese; established 16 corporate standards; and trained 30 Masterstudents, 10 PhD students, and 1 postdoctoral fellowssince 2001.

Research Team：
This research center has a staff of 16, including 2 professors, 4 associate professors and 5 research associates. Among them, 6 got doctoral degrees and 4 got master's degrees. Beside there are 3 Post-Doctors, 1 Ph.Dcandidate and 3 Master students in this center. It composes of people from different subjects including entomology, microbiology, molecular biology, biochemistry, biological fermentation engineering, pest management and so on.

Principle Investigator: Professor Richou Han
Tel:8620-89103943, 8620-84191089
Email: hanrc@ giabr.gd.cn

Publications in recent five years（2012-2017）:
1.Guo WX, Yan X, Han RC. Adapted formulations for entomopathogenic nematodes, Steinernema andHeterorhabditisspp.Nematology, 2017, doi:10.1163/15685411-00003072.
2.Guo WX, Yan X, Zhao GY, Han RC. Increased efficacy of entomopathogenic nematode-insecticide combinations against Holotrichiaoblita. Journal of Economic Entomology, 2017,110(1): 41-51.
3.Liu G, Qiu X, Cao L, Zhang Y, Han R. Evaluation of reference genes for reverse transcription quantitative PCR Studies of physiological responses in the ghost moth, Thitarodesarmoricanus(Lepidoptera, Hepialidae). PLOS ONE, 2016, 11(7): e0159060.
4.Zhang J, Zhang Y, Han R. The high-throughput production of dsRNA against sacbrood virus for use in the honey bee Apiscerana (Hymenoptera: Apidae). Virus Genes. 2016, 52(5): 698-705.
5.Zhan Z, Qiu X, Han R. Horizontal transfer of the C-termini of tccC genes in Photorhabdus and Xenorhabdus. Genes & Genomics, 2016, 38(8): 685-692.
6.Qiu X, Wu C, Cao L, Ehlers RU, Han R.Photorhabdusluminescens LN2 requires rpoS for nematicidal activity and nematode development.FEMS Microbiology Letters, 2016, 363(6): doi: 10.1093/femsle/fnw035.
7.Yan X, Waweru B, Qiu X, Hategekimana A, Kajuga J, Li H, Edgington S, Umulisa C, Han R, Toepfer S. New entomopathogenic nematodes from semi natural and small-holder farming habitats of Rwanda, Biocontrol Science and Technology, 2016, 26 (6): 820-834.
8.Tao Z, Cao L, Zhang Y, Ye Y, Han R. Laboratory Rearing of Thitarodesarmoricanus and Thitarodesjianchuanensis (Lepidoptera: Hepialidae), Hosts of the Chinese Medicinal Fungus Ophiocordycepssinensis (Hypocreales: Ophiocordycipitaceae). Journal of Economic Entomology, 2016, 109(1): 176-781.
9.Cao L, Ye Y, Han R. Fruiting body production of the medicinal Chinese caterpillar mushroom, Ophiocordycepssinensis (Ascomycetes), in artificial medium. International Journal of Medicinal Mushrooms, 2015, 17(11): 1017–1022.
10.Jiang K. Han R. Rhf1 gene is involved in the fruiting body production of Cordycepsmilitaris fungus. Journal of Industrial Microbiology & Biotechnology, 2015, 42(8): 1183–1196.
11.Zheng Z, Qiu X. Han R. Identification of the genes involved in the fruiting body production and cordycepin formation of Cordycepsmilitaris Fungus. Mycobiology, 2015, 43(1): 37-42.
12.Guo W, Yan X, Zhao G, Chen J, Han R. Efficacy of entomopathogenicSteinernema and Heterorhabditis nematodes against Holotrichiaoblita.        Journal of Pest Science, 2015, 88: 359-368.
13.Zhang Y, Zhang G, Huang X, Han R. Proteomic analysis of Apiscerana and Apismelliferalarvae fed with Heterospecific Royal Jelly and by CSBV challenge.PLoS ONE, 2014, 9(8): e102663.
14.Fayyaz S, Yan X, Qiu L, Han R, Gulsher M, Khanum TA, Javed S. A new entomopathogenic nematode, Steinernemabifurcatumn. sp. (Rhabditida: Steinernematidae) from Punjab, Pakistan. Nematology, 2014, 16: 821-836.
15.Qiu X, Zhan Z, Yan X, Han R. Draft Genome sequence and annotation of the entomopathogenicbacterium Photorhabdusluminescens LN2, which shows nematicidalactivity against HeterorhabditisbacteriophoraH06 nematodes. Genome Announcement, 2014, 2(6): e01268-14.
16.Yan X, Wang X, Han R, Qiu X. Utilisation of entomopathogenic nematodes, Heterorhabditisspp.andSteinernema spp., for the control of Agrotisipsilon(Lepidoptera, Noctuidae) in China. Nematology, 2014, 16(1): 31-40.
17.Zhang Y, Huang X, Xu Z, Han R, Chen J. Differential gene transcription in honeybee (Apiscerana) larvae challenged by Chinese Sacbrood Virus (CSBV). Sociobiology, 2013, 60(4): 413-420.
18.Mei C, Zhang Y, Mao X, Jiang K, Cao L, Yan X, Han R. The effects of culture parameters on the conidial germination and yields of Ophiocordycepssinensis. Journal of Yeast and Fungal Research, 2013, 4(4): 44-51.
19.Guo W, Yan X, Zhao G, Han R. Efficacy of entomopathogenicSteinernema and Heterorhabditis nematodes against white grubs (Coleoptera: Scarabaeidae) in peanut fields. Journal of Economic Entomology, 2013, 106(3): 1112-1117.
20.Zhang Y, Zhao Y, Qiu X, Han R. Differentially expressed genes of Coptotermesformosanus (Isoptera: Rhinotermitidae) challenged by chemical insecticides. Journal of Economic Entomology, 2013, 106(4): 1863-1870.
21.Yan X, Han R, Moens M, Chen SL, De Clercq P. Field evaluation of entomopathogenic nematodes for biological control of striped flea beetle, Phyllotretastriolata (Coleoptera: Chrysomelidae). BioControl, 2013, 58: 247-256.
22.Ma J, Chen S, Moens M, De Clercq P, Li X, Han R. Characterization in biological traits of entomopathogenic nematodes isolated from North China. Journal of Invertebrate Pathology, 2013, 114(3): 268-276.
23.Ma J, Chen S, Moens M, Han R, De Clercq P. Efficacy of entomopathogenic nematodes (Rhabditida: Steinernematidae and Heterorhabditidae) against the chive gnat, Bradysiaodoriphaga. Journal of Pest Science, 2013, 86:551-561.
24.Yan X, Moens M, Han R, Chen SL, De Clercq P. Effects of selected insecticides on osmotically treated entomopathogenic nematodes. Journal of Plant Diseases and Protection, 2012, 119(4): 152-158.
25.Yan X, Han R, Chen S, Moens M, De Clercq P. Differential gene expression after osmotic induction in various species of entomopathogenic nematodes. Russian Journal of Nematology, 2012, 20(2): 167-170.
26.Shapiro-Ilan DI, Han RC, Dolinksi C. Entomopathogenic nematode production and application technology. Journal of Nematology, 2012, 44(2): 206-217.
27.Qiu X, Yan X, Liu M, Han R. Genetic and proteomic characterization of rpoB mutations and their effect on nematicidal activity in Photorhabdusluminescens LN2. PLoS ONE, 2012, 7(8): e43114.
28.Ai H, Yan X, Han R. Occurrence and prevalence of seven bee viruses in Apismellifera and Apiscerana apiaries in China. Journal of Invertebrate Pathology, 2012, 109 (1): 160-164.
29.Zheng Z, Jiang K, Huang C, Mei C, Han R. Cordycepsmilitaris (Hypocreales: Cordycipitaceae): transcriptional analysis and molecular characterization of cox1 and group I intron with putative LAGLIDADG endonuclease. World Journal of Microbiology and Biotechnology, 2012, 28(1): 371-380.